HA Carnosina

The aim of the project is the research and development of a new product: the bio-conjugate of hyaluronic acid (HA) with carnosine, as a pharmaceutical ingredient. During the project, industrial research and experimental development will be carried out with the aim of producing and characterizing the new active ingredient and developing at least one formulation (oral or intra-articular) for the treatment of osteoarticular pathologies and a medical device for the treatment of skin ulcers. In addition to the chemical-physical and pharmacological characterization, to the study of the molecule's action mechanism and its effectiveness in the treatment of the above mentioned pathologies, all preclinical activities in GLP, of in vivo toxicity, and the validation of the production process will be carried out. according to the CGMP necessary for obtaining the production authorization of the new pharmaceutical active ingredient.